Publication Search Results
- Card, K. J., T. LaBar, J. B. Gomez, and R. E. Lenski. 2019. Historical contingency in the evolution of antibiotic resistance after decades of relaxed selection. PLOS Biology, in press. (Open access) [doi:10.5061/dryad.g41hg96]
- Lamrabet, O., J. Plumbridge, M. Martin, R. E. Lenski, D. Schneider, and T. Hindré. 2019. Plasticity of promoter-core sequences allows bacteria to compensate for the loss of a key global regulatory gene. Molecular Biology and Evolution 36: 1121-1133. (Paper) [10.5061/dryad.d02sc44]
- Blount, Z. D., R. E. Lenski, and J. B. Losos. 2018. Contingency and determinism in evolution: replaying life’s tape. Science 362: 655 (review summary) and Science 362: eaam5979 (full review article). (Review Summary)
- Peng, F., S. Widmann, A. Wünsche, K. Duan, K. A. Donovan, R. C. J. Dobson, R. E. Lenski, and T. F. Cooper. 2018. Effects of beneficial mutations in pykF gene vary over time and across replicate populations in a long-term experiment with bacteria. Molecular Biology and Evolution 35: 202-210. (Abstract)
- Good, B. H., M. J. McDonald, J. E. Barrick, R. E. Lenski, and M. M. Desai. 2017. The dynamics of molecular evolution over 60,000 generations. Nature 551: 45-50.
(Abstract)
- Meyer, J. R., D. T. Dobias, S. J. Medina, L. Servilio, A. Gupta, and R. E. Lenski. 2016. Ecological speciation of bacteriophage Lambda in allopatry and sympatry. Science 354:1301-1304.
(Abstract)[10.5061/dryad.4qb79]
- Burmeister, A. R., R. E. Lenski, and J. R. Meyer. 2016. Host coevolution alters the adaptive landscape of a virus. Proceedings of the Royal Society, London B 283: 20161528. (Article)[10.5061/dryad.2tj43]
- Lenski, R. E., M. J. Wiser, N. Ribeck, Z. D. Blount, J. R. Nahum, J. J. Morris, L. Zaman, C. B. Turner, B. D. Wade, R. Maddamsetti, A. R. Burmeister, E. J. Baird, J. Bundy, N. A. Grant, K. J. Card, M. Rowles, K. Weatherspoon, S. E. Papoulis, R. Sullivan, C. Clark, J. S. Mulka, and N. Hajela. 2015. Sustained fitness gains and variability in fitness trajectories in the long-term evolution experiment with Escherichia coli. Proceedings of the Royal Society, London B 282:20152292. (Article)[doi:10.5061/dryad.gd3dq]
- Maddamsetti, R., R. E. Lenski, and J. E. Barrick. 2015. Adaptation, clonal interference, and frequency-dependent interactions in a long-term evolution experiment with Escherichia coli. Genetics 200:619-631. (Abstract)[10.5061/dryad.3m00k]
- Ostrowski, E. A., C. Ofria, and R. E. Lenski. 2015. Genetically integrated traits and rugged adaptive landscapes in digital organisms. BMC Evolutionary Biology 15:83. (Article)[10.5061/dryad.hh650]
- Plucain, J., T. Hindré, M. Le Gac, O. Tenaillon, S. Cruveiller, C. Médigue, N. Leiby, W. R. Harcombe, C. J. Marx, R. E. Lenski, D. Schneider. 2014. Epistasis and allele specificity in the emergence of a stable polymorphism in Escherichia coli. Science 343:1366-1369. (Full Text PDF)[doi:10.5061/dryad.12c6b]
- Wiser, M. J., N. Ribeck, and R. E. Lenski. 2013. Long-term dynamics of adaptation in asexual populations. Science 342:1364-1367. (Full Text PDF)[doi:10.5061/dryad.0hc2m]
- Covert, A. W. III, R. E. Lenski, C. O. Wilke, and C. Ofria. 2013. Experiments on the role of deleterious mutations as stepping stones in adaptive evolution. Proceedings of the National Academy of Sciences, USA 110: E3171-E3178. (Abstract)[doi:10.5061/dryad.4hp5n]
- Blount, Z. D., J. E. Barrick, C. J. Davidson, and R. E. Lenski. 2012. Genomic analysis of a key innovation in an experimental Escherichia coli population. Nature 489:513-518.
(Abstract)[doi:10.5061/dryad.8q6n4]
- Zaman, L., C. Ofria, and R. E. Lenski. 2012. Finger-painting fitness landscapes: an interactive tool for exploring complex evolutionary dynamics. Pp. 499-505 in Thirteenth International Conference on the Simulation and Synthesis of Living Systems. (Abstract)
- Meyer, J. R., D. T. Dobias, J. S. Weitz, J. E. Barrick, R. T. Quick, and R. E. Lenski. 2012. Repeatability and contingency in the evolution of a key innovation in phage Lambda. Science 335:428-432.
(Abstract)[doi:10.5061/dryad.sh7rm2pt]
- Khan, A. I., D. M. Dinh, D. Schneider, R. E. Lenski, and T. F. Cooper. 2011. Negative epistasis between beneficial mutations in an evolving bacterial population. Science 332:1193-1196.
(Abstract)[doi:10.5061/dryad.5rv40]
- Woods, R. J., J. E. Barrick, T. F. Cooper, U. Shrestha, M. R. Kauth, and R. E. Lenski. 2011. Second-order selection for evolvability in a large Escherichia coli population. Science 331:1433-1436. (Abstract)
- Crozat, E., T. Hindré, L. Kühn, J. Garin, R. E. Lenski, and D. Schneider. 2011. Altered regulation of the OmpF porin by Fis in Escherichia coli during an evolution experiment and between B and K12 strains. Journal of Bacteriology 193:429-440. (Abstract)
- Strelioff, C. C., R. E. Lenski, and C. Ofria. 2010. Evolutionary dynamics, epistatic interactions, and biological information. Journal of Theoretical Biology 266:584-594. (Abstract)
- Barrick, J. E., M. R. Kauth, C. C. Strelioff, and R. E. Lenski. 2010. Escherichia coli rpoB mutants have increased evolvability in proportion to their fitness defects. Molecular Biology and Evolution 27:1338-1347. (Abstract)
- Blount, Z. D., C. Z. Borland, and R. E. Lenski. 2008. Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coli. Proceedings of the National Academy of Sciences, USA 105:7899-7906. (Abstract)(Acrobat file)
- Cooper, T. F., S. K. Remold, R. E. Lenski, and D. Schneider. 2008. Expression profiles reveal parallel evolution of epistatic interactions involving the CRP regulon in Escherichia coli. PLoS Genetics 4:e35 [10 pp]. (Article)
- Beerenwinkel, N., L. Pachter, B. Sturmfels, S. F. Elena, and R. E. Lenski. 2007. Analysis of epistatic interactions and fitness landscapes using a new geometric approach. BMC Evolutionary Biology 7:60 [12 pp]. (Article)
- Elena, S. F., C. O. Wilke, C. Ofria, and R. E. Lenski. 2007. Effects of population size and mutation rate on the evolution of mutational robustness. Evolution 61:666-674. (Abstract)
- Misevic, D., C. Ofria, R. E. Lenski. 2006. Sexual reproduction reshapes the genetic architecture of digital organisms. Proceedings of the Royal Society, London B 273:457-464. (Link to PDF)
- Cooper, T. F., R. E. Lenski, and S. F. Elena. 2005. Parasites and mutational load: an experimental test of a pluralistic theory for the evolution of sex. Proceedings of the Royal Society, London B 272:311-317. (Article)
- Misevic, D., R. E. Lenski, and C. Ofria. 2004. Sexual reproduction and Muller's ratchet in digital organisms. Pp. 340-345 in J. Pollack, M. Bedau, P. Husbands, T. Ikegami, and R. A. Watson, eds. Artificial Life IX: Proceedings of the Ninth International Conference on the Simulation and Synthesis of Living Systems. MIT Press, Cambridge, Massachusetts. (Acrobat file)
- Remold, S. K., and R. E. Lenski. 2004. Pervasive joint influence of epistasis and plasticity on mutational effects in Escherichia coli. Nature Genetics 36:423-426. (Nature Genetics)(Acrobat file)
- Wilke, C. O., R. E. Lenski, and C. Adami. 2003. Compensatory mutations cause excess of antagonistic epistasis in RNA secondary structure folding. BMC Evolutionary Biology 3:3. (Link)
- Cooper, T. F., D. E. Rozen, and R. E. Lenski. 2003. Parallel changes in gene expression after 20,000 generations of evolution in Escherichia coli. Proceedings of the National Academy of Sciences, USA 100:1072-1077. (Abstract)(Acrobat file)
- Lenski, R. E. 2001. Come fly, and leave the baggage behind (Perspective). Science 294:533-534. (Reprint)(Acrobat file)
- Elena, S. F., and R. E. Lenski. 2001. Epistasis between new mutations and genetic background and a test of genetic canalization. Evolution 55:1746-1752. (Abstract)(Acrobat file)
- Remold, S. K., and R. E. Lenski. 2001. Contribution of individual random mutations to genotype-by-environment interactions in Escherichia coli. Proceedings of the National Academy of Sciences, USA 98:11388-11393. (Abstract)(Acrobat file)
- Wilke, C. O, J. Wang, C. Ofria, R. E. Lenski, and C. Adami. 2001. Evolution of digital organisms at high mutation rate leads to survival of the flattest. Nature 412:331-333. (Abstract)(Acrobat file)
- Moore, F. B-G., D. E. Rozen, and R. E. Lenski. 2000. Pervasive compensatory adaptation in Escherichia coli. Proceedings of the Royal Society, London B, 267:515-522. (Abstract)(Acrobat file)
- Lenski, R. E., C. Ofria, T. C. Collier, and C. Adami. 1999. Genome complexity, robustness, and genetic interactions in digital organisms. Nature 400:661-664. (Link)(Acrobat file)
- Bohannan, B. J. M., M. Travisano, and R. E. Lenski. 1999. Epistatic interactions can lower the cost of resistance to multiple consumers. Evolution 53:292-295. (Abstract)(Acrobat file)
- Elena, S. F., L. Ekunwe, N. Hajela, S. A. Oden, and R. E. Lenski. 1998. Distribution of fitness effects caused by random insertion mutations in Escherichia coli. Genetica 102/103:349-358. (Abstract)(Acrobat file)
- Elena, S. F., and R. E. Lenski. 1997. Test of synergistic interactions among deleterious mutations in bacteria. Nature 390:395-398.
(Abstract)(Acrobat file) [doi:10.5061/dryad.rg8mb]
- Lenski, R. E., V. Souza, L. P. Duong, Q. G. Phan, T. N. M. Nguyen, and K. P. Bertrand. 1994. Epistatic effects of promoter and repressor functions of the Tn10 tetracycline-resistance operon on the fitness of Escherichia coli. Molecular Ecology 3:127-135. (Acrobat file)
- Lenski, R. E. 1988. Experimental studies of pleiotropy and epistasis in Escherichia coli. II. Compensation for maladaptive pleiotropic effects associated with resistance to virus T4. Evolution 42:433-440. (Acrobat file)
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