Genomics data from the long-term evolution experiment
Genome sequence of the ancestral strain, REL606, a derivative of E. coli B:
- Complete REL606 genome sequence deposited in GenBank
- Complete REL607 genome sequence
- First 2009 J Mol Bio paper describing historical derivation of E. coli B
- Second 2009 J Mol Bio paper presenting genome sequence of REL606
- Third 2009 J Mol Bio paper comparing genome sequences of REL606, another B derivative, and E. coli K-12
Whole-genome alignment of E. coli K-12 MG1655 and E. coli B REL606 from Jeong et al. (2009).
Genome sequences of evolved clones from 2,000 to 40,000 generations of line Ara-1:
- Raw sequence reads for seven clonal genomes archived at NCBI
- 2009 Nature paper analyzing the dynamics of genome evolution
- Supplementary tables showing molecular details of all SNP and DIP mutations in clonal genomes
Mutations in evolving genomes from generations 2,000 to 40,000 from Barrick et al. (2009)
Genomic analysis of point-mutational polymorphisms in whole-population samples from 2,000 to 40,000 generations of line Ara-1:
- Raw sequence reads for seven whole-population samples archived at NCBI
- CSHSQB paper analyzing the dynamics of within-population mutational diversity
- Supplementary tables showing all SNPs predicted in whole-population samples<
Schematic illustration of mutational diversity in an evolving E. coli population from Barrick and Lenski (in press)